Natural
anti‑aging
actives

INSPIRED BY PATAGONIAN YEASTS

About

bio h41 is a biotechnology startup based in Bariloche, Argentina, born from the collaboration between Grupo Harmony and IPATEC (CONICET-UNCo). We develop natural active ingredients for skin care and sun care, obtained by fermentation of native Patagonian yeasts. Our first product, Rhodoboost™, absorbs UV-B radiation, acts as an antioxidant and visibly reduces wrinkles.

Our products

Rhodoboost™

A natural anti-aging dried active from the yeast Phaffia rhodozyma. Its key compound, MGG, absorbs UV-B radiation and neutralizes reactive oxygen species. In a 4-week clinical study, 100% of panelists showed a 22% reduction in wrinkle depth. For skin care and sun care formulations.

Rhodoboost ATX · in development

Rhodoboost with astaxanthin, a well-known natural antioxidant, for well-aging skin care.

RhodoPure · in development

High-purity MGG for next-generation UV-B protection.

Clinical results

Rhodoboost™ was tested at 5% in a gel and compared with the same gel without it. Fifteen women aged 37 to 67 applied it to the face twice a day for 4 weeks. Measurements were instrumental and non-invasive.

−22%

Wrinkle depth

100% of panelists showed a 22% reduction in wrinkle depth.

+67%

Skin energy

80% of panelists reported a 67% increase in perceived skin energy.

−20%

Skin stress

93% of panelists showed a 20% decrease in skin stress and fatigue markers.

Study performed by About-Claim following international standard procedures.

Request the technical brochure

Science

The science

Rhodoboost™ is the result of more than 20 years of research at IPATEC (CONICET-UNCo) on yeasts from Patagonia, where high UV radiation shaped how these microorganisms protect themselves.

MGG, a mycosporine

Mycosporine-glutaminol-glucoside is the compound the yeast Phaffia rhodozyma produces to protect itself from sunlight. It absorbs UV-B radiation, with a peak at 310 nm.

Photostable

Under light exposure MGG degrades far less than octinoxate: photodegradation quantum yield of 1.1 × 10⁻⁵, versus 2 × 10⁻² for octinoxate.

Antioxidant

MGG quenches singlet oxygen at rates similar to vitamins C and E.

Clean process

Produced by fermentation and purified with a solvent-free downstream process.

Backed by

IPATEC (CONICET-UNCo)

Research partner and origin of the MGG technology. Part of CONICET, Argentina’s national research council, and the Universidad Nacional del Comahue.

Grupo Harmony

Commercial and industrial partner.

Our team

A team that connects science, technology and business: researchers from IPATEC-CONICET, bioprocess experts and the industrial experience of Grupo Harmony.